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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TARDBP
All Species:
10.61
Human Site:
S379
Identified Species:
29.17
UniProt:
Q13148
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13148
NP_031401.1
414
44740
S379
N
S
Y
S
G
S
N
S
G
A
A
I
G
W
G
Chimpanzee
Pan troglodytes
XP_001135126
357
37996
G323
S
Y
S
G
S
N
S
G
A
A
I
G
W
G
S
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q921F2
414
44529
S379
N
S
Y
S
G
S
N
S
G
A
P
L
G
W
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515386
295
33249
E261
S
V
H
I
S
N
A
E
P
K
H
N
S
N
R
Chicken
Gallus gallus
Q5ZLN5
414
44571
S379
N
S
Y
G
G
S
N
S
G
A
A
I
G
W
G
Frog
Xenopus laevis
Q6NU14
291
32937
G257
D
Y
S
G
Y
N
Y
G
N
Y
G
Y
N
Q
G
Zebra Danio
Brachydanio rerio
NP_958884
412
44409
S377
N
S
N
Y
G
S
S
S
A
A
L
G
W
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392590
466
50438
M419
N
S
G
F
L
S
W
M
N
Q
G
G
G
D
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q99383
534
59631
R496
R
D
R
G
D
R
D
R
N
D
R
D
R
D
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
N.A.
N.A.
N.A.
96.1
N.A.
N.A.
66.6
95.1
22.7
76
N.A.
N.A.
49.5
N.A.
N.A.
Protein Similarity:
100
86.2
N.A.
N.A.
N.A.
98.7
N.A.
N.A.
69.5
97.3
38.4
86.4
N.A.
N.A.
63
N.A.
N.A.
P-Site Identity:
100
6.6
N.A.
N.A.
N.A.
86.6
N.A.
N.A.
0
93.3
6.6
40
N.A.
N.A.
33.3
N.A.
N.A.
P-Site Similarity:
100
26.6
N.A.
N.A.
N.A.
93.3
N.A.
N.A.
20
93.3
20
46.6
N.A.
N.A.
33.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
23.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
38.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
12
0
23
56
23
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
12
12
0
0
12
0
12
0
0
12
0
12
0
23
0
% D
% Glu:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
12
45
45
0
0
23
34
0
23
34
45
23
56
% G
% His:
0
0
12
0
0
0
0
0
0
0
12
0
0
0
0
% H
% Ile:
0
0
0
12
0
0
0
0
0
0
12
23
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
12
0
0
0
0
0
% K
% Leu:
0
0
0
0
12
0
0
0
0
0
12
12
0
0
0
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% M
% Asn:
56
0
12
0
0
34
34
0
34
0
0
12
12
12
0
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
12
0
0
0
12
0
% Q
% Arg:
12
0
12
0
0
12
0
12
0
0
12
0
12
0
12
% R
% Ser:
23
56
23
23
23
56
23
45
0
0
0
0
12
0
12
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% T
% Val:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
12
0
0
0
0
0
23
34
0
% W
% Tyr:
0
23
34
12
12
0
12
0
0
12
0
12
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _